The San Francisco 49ers travel south to play at the Los Angeles Rams, with an early first-place lead in the NFC West Division on the line in one of the key contests for Week 2 of the NFL season.
The matchup between the two 1-0 teams can be seen on FOX and the FOX Sports App at 4:05 p.m. ET on Sunday.
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The Super Bowl champion Kansas City Chiefs look to return to their winning ways after losing to the Detroit Lions 21-20 in the season-opening game Thursday night.
The Chiefs will play at the 1-0 Jacksonville Jaguars on Sunday in a rematch of last season’s AFC divisional round match, a 27-20 victory for Kansas City.
Here’s everything you need to know about the NFL odds for Week 2 — the point spread, moneyline, total Over/Under, experts’ picks and final betting results.
All times ET
SUNDAY’S GAMES
Packers at Falcons (1 p.m., FOX and FOX Sports App)
Point spread: Falcons -2 (Falcons favored to win by more than 2 points, otherwise Packers cover)
Moneyline: Falcons -130 favorites to win (bet $10 to win $17.69 total); Packers +110 underdogs to win (bet $10 to win $21 total)
Total scoring Over/Under: 40 points scored by both teams combined
Pick via FOX Sports Betting Analyst Geoff Schwartz:
I just don’t buy the Falcons being any good after Week 1.
They beat the Carolina Panthers 24-10 with only 13 offensive first downs and 221 yards. They forced three turnovers and scored 17 points on short fields. Their defense was active, getting after Panthers rookie quarterback Bryce Young, but the Falcons are not going to force three turnovers against the Packers.
The Packers looked like a playoff team against the Chicago Bears on Sunday. Jordan Love is finally the Packers’ starting quarterback of the future, and he played the part in their win. He was cool, calm and collected while playing within himself and the system.
The Packers defense was active and made it difficult for the Bears’ offense to operate.
The Pack are just better than the Falcons, and I’m fine laying a point with them on the road.
PICK: Packers (-1) to win by more than 1 point (At time of pick)
Pick via FOX Sports Betting Analyst Sam Panayotovich:
There aren’t many bigger Falcons fans than me this year. And no, I’m not from Atlanta.
Bijan Robinson is an absolute game-changer for the Falcons and his presence makes life easier on everybody else involved. The rookie from Texas touched the ball 16 times for 83 yards and a score, and it feels like his usage will only increase as the season progresses.
Green Bay will be a very popular look here after drubbing the Bears 38-20 in Chicago, but the Bears truly beat themselves. And the Packers surprisingly played a turnover-free game with first-year starter Jordan Love at quarterback, but this should be a season of ups-and-downs for The Cheese.
Atlanta starting cornerback Jeff Okudah and jack-of-all-trades Cordarrelle Patterson are expected back after missing Week 1 with injuries and I believe the Dirty Birds have enough to improve to 2-0.
PICK: Falcons (+1) to lose by 1 point or tie (or win outright) (At time of pick)
Seahawks at Lions (1 p.m., FOX and FOX Sports App)
Point spread: Lions -4.5 (Lions favored to win by more than 4.5 points, otherwise Seahawks cover)
Moneyline: Lions -218 favorites to win (bet $10 to win $14.59 total); Seahawks +180 underdogs to win (bet $10 to win $28 total)
Total scoring Over/Under: 47.5 points scored by both teams combined
Pick via FOX Sports Betting Analyst Sam Panayotovich:
In just one week, Seattle went from a supposed NFC West contender to a team that might be in a whole lot of trouble on both sides of the ball.
The Seahawks lost both starting offensive tackles last week against the Rams and their availability for Sunday doesn’t sound too promising, per head coach Pete Carroll. Wide receiver Tyler Lockett also exited with a concussion.
It’s worth noting that Matthew Stafford cooked Seattle’s defense for 334 yards through the air and the Rams pasted the Seahawks 23-0 in the second half with star receiver Cooper Kupp in street clothes. Yikes!
Jared Goff’s offensive line is much better than Stafford’s and the Lions’ weapons are better across the board, too. Look out whenever Dan Campbell finds out how to use rookie joystick Jahmyr Gibbs. I refuse to overthink this one.
Lay the lumber with Detroit.
PICK: Lions (-4.5) to win by more than 4.5 points
Bears at Buccaneers (1 p.m., FOX and FOX Sports App)
Point spread: Buccaneers -2.5 (Buccaneers favored to win by more than 2.5 points, otherwise Bears cover)
Moneyline: Buccaneers -142 favorites to win (bet $10 to win $17.04 total); Bears +120 underdogs to win (bet $10 to win $22 total)
Total scoring Over/Under: 41 points scored by both teams combined
Pick via FOX Sports Betting Analyst Sam Panayotovich:
I don’t think many of us had Tampa Bay 1-0 and Chicago 0-1. Pat yourself on the back if you did.
Chicago’s offense failed to make any tangible second-half adjustments in an embarrassing home loss to rival Green Bay and I hope the offensive staff spent the last four days at the drawing board.
Let’s give Tampa Bay credit for upsetting Minnesota at the Death Star, but let’s also not get too carried away. The Bears were a 2-point favorite on the Las Vegas look ahead line and now the Bucs are laying almost a field goal? These are the Week 2 spots that get bettors in trouble.
Plug your nose and take the points.
PICK: Bears (+2.5) to lose by fewer than 2.5 points (or win outright)
Colts at Texans (1 p.m., FOX and FOX Sports App)
Point spread: Texans -1 (Texans favored to win by more than 1 points, otherwise Colts cover)
Moneyline: Texans -118 favorites to win (bet $10 to win $18.47 total); Colts -102 underdogs to win (bet $10 to win $19.80 total)
Total scoring Over/Under: 39.5 points scored by both teams combined
Raiders at Bills (1 p.m., CBS)
Point spread: Bills -8.5 (Bills favored to win by more than 8.5 points, otherwise Raiders cover)
Moneyline: Bills -395 favorites to win (bet $10 to win $12.53 total); Raiders +310 underdogs to win (bet $10 to win $41 total)
Total scoring Over/Under: 47 points scored by both teams combined
Ravens at Bengals (1 p.m., CBS)
Point spread: Bengals -3 (Bengals favored to win by more than 3 points, otherwise Ravens cover)
Moneyline: Bengals -166 favorites to win (bet $10 to win $16.02 total); Ravens +140 underdogs to win (bet $10 to win $24 total)
Total scoring Over/Under: 46 points scored by both teams combined
Chargers at Titans (1 p.m., CBS)
Point spread: Chargers -2.5 (Chargers favored to win by more than 2.5 points, otherwise Titans cover)
Moneyline: Chargers -142 favorites to win (bet $10 to win $17.04 total); Titans +120 underdogs to win (bet $10 to win $22 total)
Total scoring Over/Under: 45.5 points scored by both teams combined
Chiefs at Jaguars (1 p.m., CBS)
Point spread: Chiefs -3.5 (Chiefs favored to win by more than 3.5 points, otherwise Jaguars cover)
Moneyline: Chiefs -180 favorites to win (bet $10 to win $15.56 total); Jaguars +150 underdogs to win (bet $10 to win $25 total)
Total scoring Over/Under: 51 points scored by both teams combined
Pick via FOX Sports Betting Analyst Geoff Schwartz:
If Mahomes is a favorite of under three points or an underdog, it’s an automatic wager for me, and this line opened at -2.5 in the look ahead and hasn’t moved despite the outcomes from this weekend.
The Chiefs lost to the Detroit Lions 21-20, while Jacksonville beat the Indianapolis Colts 31-21. The Chiefs lost that game because 10% of Mahomes’ passes were dropped by a receiving corps that was without star tight end Travis Kelce. He may or may not play this weekend, but his status doesn’t change my wager.
The Chiefs’ offense is going to play better. The offensive line didn’t run block as it is capable of, and I expect an all-around better performance from that unit. The Jaguars’ defense is average, and the Chiefs handled them with ease twice last season.
The Chiefs’ defense played well against the Lions. It only allowed 14 points without DT Chris Jones in the lineup. Its young defensive backfield is solid, and I think it ends the season in the top third of the NFL. It will always be hard to stop Lawrence, but the Chiefs have the scheme and players to do it enough to cover this game.
And lastly, taking an angry Super Bowl championship team looking to get its first victory after playing poorly in Week 1 is a good wager.
PICK: Kansas City (-2.5) to win by more than 2.5 points (At time of pick)
49ers at Rams (4:05 p.m., FOX and FOX Sports App)
Point spread: 49ers -7.5 (49ers favored to win by more than 7.5 points, otherwise Rams cover)
Moneyline: 49ers -325 favorites to win (bet $10 to win $13.08 total); Rams +260 underdogs to win (bet $10 to win $36 total)
Total scoring Over/Under: 45.5 points scored by both teams combined
Giants at Cardinals (4:05 p.m., FOX and FOX Sports App)
Point spread: Giants -4 (Giants favored to win by more than 4 points, otherwise Cardinals cover)
Moneyline: Giants -218 favorites to win (bet $10 to win $14.59 total); Cardinals +180 underdogs to win (bet $10 to win $28 total)
Total scoring Over/Under: 39.5 points scored by both teams combined
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Jets at Cowboys (4:25 p.m., CBS)
Point spread: Cowboys -9 (Cowboys favored to win by more than 9 points, otherwise Jaguars cover)
Moneyline: Cowboys -440 favorites to win (bet $10 to win $12.27 total); Jets +340 underdogs to win (bet $10 to win $44 total)
Total scoring Over/Under: 38.5 points scored by both teams combined
Commanders at Broncos (4:25 p.m., CBS)
Point spread: Broncos -3.5 (Broncos favored to win by more than 3.5 points, otherwise Commanders cover)
Moneyline: Broncos -180 favorites to win (bet $10 to win $15.56 total); Commanders +150 underdogs to win (bet $10 to win $25 total)
Total scoring Over/Under: 38.5 points scored by both teams combined
Dolphins at Patriots (8:20 p.m., NBC)
Point spread: Dolphins -2.5 (Dolphins favored to win by more than 2.5 points, otherwise Patriots cover)
Moneyline: Dolphins -148 favorites to win (bet $10 to win $16.76 total); Patriots +124 underdogs to win (bet $10 to win $22.40 total)
Total scoring Over/Under: 46.5 points scored by both teams combined
Pick via FOX Sports Betting Analyst Sam Panayotovich:
Make sure you get 47 on the Over/Under on this one.
Most American sportsbooks are dealing 46.5, but there are multiple 47s in the market. It’s paramount that you go Under one of most key numbers in football betting. Please protect yourself against final scores like 27-20, 24-23 and 30-17 while those who go Under 46.5 kick themselves.
Bill Belichick and Vic Fangio are two of the sharpest defensive minds when it comes to taking away what offenses do well, and I expect a chess match on Sunday. It’ll also be easier to double Tyreek Hill if Jaylen Waddle (oblique) doesn’t play.
PICK: Under 47 points scored by both teams combined (At time of pick)
MONDAY’S GAMES
Saints at Panthers (7:15 p.m. ET, ESPN)
Point spread: Saints -3 (Saints favored to win by more than 3 points, otherwise Panthers cover)
Moneyline: Saints -155 favorites to win (bet $10 to win $16.45 total); Panthers +130 underdogs to win (bet $10 to win $23 total)
Total scoring Over/Under: 39.5 points scored by both teams combined
Browns at Steelers (8:15 p.m. ET, ABC/ESPN+)
Point spread: Browns -2.5 (Browns favored to win by more than 2.5 points, otherwise Steelers cover)
Moneyline: Browns -142 favorites to win (bet $10 to win $17.045 total); Steelers +120 underdogs to win (bet $10 to win $22 total)
Total scoring Over/Under: 38.5 points scored by both teams combined
Pick via FOX Sports Betting Analyst Geoff Schwartz:
The Cleveland Browns’ offense ran the ball well against the Bengals, but it wasn’t until the Bengals’ defense got worn down — without any help from their offense — that we saw the scoring result.
Deshaun Watson, who the Browns were hoping would return to his Houston form, did not appear to be much better in Week 1 than last season. He skipped too many footballs and didn’t throw accurate passes. Maybe it was the rain, but I’d be worried if I were Cleveland.
The Steelers’ defense is far better than it played against the San Francisco 49ers, and with the Browns down their right tackle, the Steelers’ T.J. Watt could have another big day. They will make it hard for the Browns to move the ball if Watson isn’t throwing well.
I was super bummed about the Steelers’ offense on Sunday against the 49ers. I was high on its capability in 2023, but Pittsburgh got its butt whooped by the 49ers defense. The offensive line was poor, and I hate this matchup for it against a Browns defensive line that is elite and rolls multiple layers deep.
The Steelers are going to struggle to move the ball.
I’m taking the Under here.
PICK: Under 40 points scored by both teams combined (At time of pick)
COMPLETED GAME
Point spread: Vikings (+6.5) cover by losing by fewer than 6.5 points (6)
Moneyline: Eagles win as -270 favorites (bet $10 to win $13.70 total); Vikings were +220 underdogs (bet $10 to win $32 total)
Total scoring Over/Under: Over 48.5 points scored by both teams combined (62)
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