2023 NFL Week 4 odds, predictions: Picks, lines, spreads for every game

Week 4 is here!

Tua Tagovailoa and the Miami Dolphins (3-0) travel north to Buffalo to take on the 2-1 Bills on Sunday, with first place in the AFC East Division at stake.

Josh Allen and the Bills will look to continue their recent dominance over the Dolphins. Buffalo has won 11 of the past 13 games against Miami, but the Dolphins lead the all-time series 62-56-1.

And then there’s a tantalizing matchup of NFL franchises with a combined 11 Super Bowl titles, when the New England Patriots (six championships) play at the Dallas Cowboys (five) at 4:25 p.m. ET on Sunday (FOX and FOX Sports App).

Here’s everything you need to know about the NFL odds for Week 4 — the point spread, moneyline, total Over/Under and betting results.

All times ET

SUNDAY’S GAMES

Falcons vs. Jaguars at London (9:30 a.m., ESPN+)

Point spread: Jaguars -3 (Jaguars favored to win by more than 3 points, otherwise Falcons cover)
Moneyline: Jaguars -176 favorites to win (bet $10 to win $15.68 total); Falcons +148 underdogs to win (bet $10 to win $24.80 total)
Total scoring Over/Under: 43 points scored by both teams combined

Bengals at Titans (1 p.m., FOX and FOX Sports App)

Point spread: Bengals -2.5 (Bengals favored to win by more than 2.5 points, otherwise Titans cover)
Moneyline: Bengals -154 favorites to win (bet $10 to win $16.49 total); Titans +130 underdogs to win (bet $10 to win $23 total)
Total scoring Over/Under: 41 points scored by both teams combined

Rams at Colts (1 p.m., FOX and FOX Sports App)

Point spread: Colts -1 (Colts favored to win by more than 1 point, otherwise Rams cover)
Moneyline: Colts -108 co-favorites to win (bet $10 to win $19.26 total); Rams -108 co-favorites to win (bet $10 to win $19.26 total)
Total scoring Over/Under: 45.5 points scored by both teams combined

Buccaneers at Saints (1 p.m., FOX and FOX Sports App)

Point spread: Saints -3.5 (Saints favored to win by more than 3.5 points, otherwise Buccaneers cover)
Moneyline: Saints -180 favorites to win (bet $10 to win $15.56 total); Buccaneers +152 underdogs to win (bet $10 to win $25.20 total)
Total scoring Over/Under: 39.5 points scored by both teams combined

Commanders at Eagles (1 p.m., FOX and FOX Sports App)

Point spread: Eagles -8.5 (Eagles favored to win by more than 8.5 points, otherwise Commanders cover)
Moneyline: Eagles -450 favorites to win (bet $10 to win $12.22 total); Commanders +350 underdogs to win (bet $10 to win $45 total)
Total scoring Over/Under: 43.5 points scored by both teams combined

Vikings at Panthers (1 p.m., FOX and FOX Sports App

Point spread: Vikings -4.5 (Vikings favored to win by more than 4.5 points, otherwise Panthers cover)
Moneyline: Vikings -215 favorites to win (bet $10 to win $14.65 total); Panthers +180 underdogs to win (bet $10 to win $28 total)
Total scoring Over/Under: 46.5 points scored by both teams combined

Dolphins at Bills (1 p.m., CBS)

Point spread: Bills -3 (Bills favored to win by more than 3 points, otherwise Dolphins cover)
Moneyline: Bills -152 favorites to win (bet $10 to win $16.58 total); Dolphins +128 underdogs to win (bet $10 to win $22.80 total)
Total scoring Over/Under: 53.5 points scored by both teams combined

Broncos at Bears (1 p.m., CBS)

Point spread: Broncos -3.5 (Broncos favored to win by more than 3.5 points, otherwise Bears cover)
Moneyline: Broncos -154 favorites to win (bet $10 to win $16.49 total); Bears +130 underdogs to win (bet $10 to win $23 total)
Total scoring Over/Under: 46.5 points scored by both teams combined

Ravens at Browns (1 p.m., CBS)

Point spread: Browns -1.5 (Browns favored to win by more than 1.5 points, otherwise Ravens cover)
Moneyline: Browns -126 favorites to win (bet $10 to win $17.94 total); Ravens +108 underdogs to win (bet $10 to win $20.80 total)
Total scoring Over/Under: 39.5 points scored by both teams combined

Steelers at Texans (1 p.m., CBS)

Point spread: Steelers -3 (Steelers favored to win by more than 3 points, otherwise Texans cover)
Moneyline: Steelers -166 favorites to win (bet $10 to win $16.02 total); Texans +140 underdogs to win (bet $10 to win $24 total)
Total scoring Over/Under: 41.5 points scored by both teams combined

Raiders at Chargers (4:05 p.m., CBS)

Point spread: Chargers -6.5 (Chargers favored to win by more than 6.5 points, otherwise Raiders cover)
Moneyline: Chargers -275 favorites to win (bet $10 to win $13.64 total); Raiders +225 underdogs to win (bet $10 to win $32.50 total)
Total scoring Over/Under: 48.5 points scored by both teams combined

Patriots at Cowboys (4:25 p.m., FOX and FOX Sports App)

Point spread: Cowboys -6.5 (Cowboys favored to win by more than 6.5 points, otherwise Patriots cover)
Moneyline: Cowboys -280 favorites to win (bet $10 to win $13.57 total); Patriots +230 underdogs to win (bet $10 to win $33 total)
Total scoring Over/Under: 43.5 points scored by both teams combined

Cardinals at 49ers (4:25 p.m., FOX and FOX Sports App)

Point spread: 49ers -14 (49ers favored to win by more than 14 points, otherwise Cardinals cover)
Moneyline: 49ers -1000 favorites to win (bet $10 to win $11 total); Cardinals +660 underdogs to win (bet $10 to win $76 total)
Total scoring Over/Under: 43.5 points scored by both teams combined

Chiefs at Jets (8:20 p.m., NBC)

Point spread: Chiefs -8.5 (Chiefs favored to win by more than 8.5 points, otherwise Jets cover)
Moneyline: Chiefs -405 favorites to win (bet $10 to win $12.47 total); Jets +320 underdogs to win (bet $10 to win $42 total)
Total scoring Over/Under: 41.5 points scored by both teams combined

MONDAY’S GAME

Seahawks at Giants (8:15 p.m., ESPN/ABC)

Point spread: Seahawks -1.5 (Seahawks favored to win by more than 1.5 points, otherwise Giants cover)
Moneyline: Seahawks -124 favorites to win (bet $10 to win $18.06 total); Giants +106 underdogs to win (bet $10 to win $20.60 total)
Total scoring Over/Under: 47.5 points scored by both teams combined

COMPLETED GAME

Lions 34, Packers 20

Point spread: Lions (-1.5) cover by winning by more than 1.5 points (14)
Moneyline: Lions win as -118 favorites (bet $10 to win $18.47 total); Packers were +100 underdogs (bet $10 to win $20 total)
Total scoring Over/Under: Over 45.5 points scored by both teams combined (54)